1. COVID-19 Vaccines/ or COVID-19/ or COVID-19 Testing/ or COVID-19 Serological Testing/ or SARS-CoV-2/ or exp coronavirus/
2. *mental health/ or exp *mental disorders/ or exp *mental processes/ or exp *anxiety disorders/ or exp *"disruptive, impulse control, and conduct disorders"/ or exp *"feeding and eating disorders"/ or exp *mood disorders/ or exp *personality disorders/ or exp *sleep wake disorders/ or exp *substance-related disorders/ or exp *"trauma and stressor related disorders"/ or exp *stress disorders, traumatic/ or hypochondriasis/ or resilience, psychological/
3. ("Alcohol abus$3" or "alcohol use$2" or Anxiety or Bereavement or Conflict$2 or Compulsion or coping or Cyberchondria or Depression or despair or "disruptive behavior" or Distress or "emotion regulation" or "financial strain" or Hypochondriasis or Isolation or Loneliness or "mental health" or mental or Mood or Obsession or "obsessive-compulsive" or "obsessive compulsive disorder" or overwhelmed or Panic or Posttraumatic or "Post trauma$3" or "prolonged grief" or Psychiatric or "psychiatric disorder" or "psychological well-being" or Psychologic or "psychological impact" or psychoses or psychosis or Ptsd or resilience or resilient or "social isolation" or Stress$3 or "substance use" or "Substance abuse" or Suicide or Suicidal or telepsychiatry or traumatic or violence or worry or "food security" or "community psychology" or fear or "self-harm" or bereavement or "death wish" or "sleep-wake disorder$1" or grief or "poor-sleep" or burnout or trichotillomania or mania$1 or traumatization or coronaphobia or phobia$1 or "impulse control" or "social support" or "moral distress").mp.
4. 1 and (2 or 3)
1. (covid-19 or SARS-CoV-2 or coronavirus).mp and Psycholog.mp.
2. (mental health or mental disorders or mental processes or anxiety disorders or "disruptive, impulse control, and conduct disorders" or "feeding and eating disorders" or mood disorders or personality disorders or sleep wake disorders or substance-related disorders or "trauma and stressor related disorders" or stress disorders, traumatic or hypochondriasis or resilience, psychological or Eating Disorders).mp
3. ("Alcohol abus$3" or "alcohol use$2" or Anxiety or Bereavement or Conflict$2 or Compulsion or coping or Cyberchondria or Depression or despair or "disruptive behavior" or Distress or "emotion regulation" or "financial strain" or Hypochondriasis or Isolation or Loneliness or "mental health" or mental or Mood or Obsession or "obsessive-compulsive" or "obsessive compulsive disorder" or overwhelmed or Panic or Posttraumatic or "Post trauma$3" or "prolonged grief" or Psychiatric or "psychiatric disorder" or "psychological well-being" or Psychologic or "psychological impact" or psychoses or psychosis or Ptsd or resilience or resilient or "social isolation" or Stress$3 or "substance use" or "Substance abuse" or Suicide or Suicidal or telepsychiatry or traumatic or violence or worry or "food security" or "community psychology" or fear or "self-harm" or bereavement or "death wish" or "sleep-wake disorder$1" or grief or "poor-sleep" or burnout or trichotillomania or mania$1 or traumatization or coronaphobia or phobia$1 or "impulse control" or "social support" or "moral distress" or "eating disorder$1").mp
4. (1 AND (2 or 3)
1. *covid-19/px or *covid-19 vaccines/px
2. exp psychological phenomena/
3. COVID-19 Vaccines/ or COVID-19/ or COVID-19 Testing/ or COVID-19 Serological Testing/ or SARS-CoV-2/
4. *mental health/ or exp *mental disorders/ or exp *mental processes/ or exp *anxiety disorders/ or exp *"disruptive, impulse control, and conduct disorders"/ or exp *"feeding and eating disorders"/ or exp *mood disorders/ or exp *personality disorders/ or exp *sleep wake disorders/ or exp *substance-related disorders/ or exp *"trauma and stressor related disorders"/ or exp *stress disorders, traumatic/ or hypochondriasis/ or resilience, psychological/ or exp "Feeding and Eating Disorders"/
5. ("Alcohol abus$3" or "alcohol use$2" or Anxiety or Bereavement or Conflict$2 or Compulsion or coping or Cyberchondria or Depression or despair or "disruptive behavior" or Distress or "emotion regulation" or "financial strain" or Hypochondriasis or Isolation or Loneliness or "mental health" or mental or Mood or Obsession or "obsessive-compulsive" or "obsessive compulsive disorder" or overwhelmed or Panic or Posttraumatic or "Post trauma$3" or "prolonged grief" or Psychiatric or "psychiatric disorder" or "psychological well-being" or Psychologic or "psychological impact" or psychoses or psychosis or Ptsd or resilience or resilient or "social isolation" or Stress$3 or "substance use" or "Substance abuse" or Suicide or Suicidal or telepsychiatry or traumatic or violence or worry or "food security" or "community psychology" or fear or "self-harm" or bereavement or "death wish" or "sleep-wake disorder$1" or grief or "poor-sleep" or burnout or trichotillomania or mania$1 or traumatization or coronaphobia or phobia$1 or "impulse control" or "social support" or "moral distress" or "eating disorder$1").ti,kw.
6. (1 and 2) or (3 and (4 or 5))
1. ((covid or covid-19 or covid19 or SARS-COV-2 or coronavirus) and (vaccine$ or vaccinating or vaccination$1 or immunization$ or immuniz$ or "herd immunity" or "anti adj vaccination")).mp
2. ((exp vaccines/ or exp vaccinations/ or vaccination refusal/ or anti-vaccination movement/ or immunization programs/ or mass vaccination/ or vaccination coverage/ or Immunity, Herd/) and (COVID-19/ or SARS-CoV-2/)) or COVID-19 vaccines/
3. 1 or 2
1. ((covid or covid19 or covid-19 or SARS-COV-2 or coronavirus) and (vaccine$ or vaccinating or vaccination$1 or "herd immunity" or "anti adj vaccination" or pfizer or astra zeneca or moderna or "Johnson & Johnson" or Janssen or bioNtech or novamax or BNT162b2 or mRNA-1273 or JNJ-78436735 or ModernaTX)).ti,ot,kw,ab.
1. ((covid or covid19 or covid-19 or SARS-COV-2 or coronavirus) and (vaccine$ or vaccinating or vaccination$1 or immunization$ or immuniz$ or "herd immunity" or "anti adj vaccination")).mp.
2. (exp coronavirus disease 2019/ or exp severe acute respiratory syndrome coronavirus 2/ or covid-19.mp. or SARS-COV-2.mp.) and (exp vaccine/ or exp vaccination/ or exp vaccination reaction/ or vaccination refusal/ or exp anti-vaccination movement/ or exp immunization/ or mass immunization/ or vaccination coverage/ or herd immunity/)
3. 1 or 2
1. exp Coronavirus/
2. exp Coronavirus Infections/
3. (coronavirus* or corona virus* or OC43 or NL63 or 229E or HKU1 or HCoV* or ncov* or covid* or sars-cov* or sarscov* or Sars-coronavirus* or Severe Acute Respiratory Syndrome Coronavirus* or "Kawasaki like paediatric inflammatory multisystem syndrome" or "Kawasaki like pediatric inflammatory multisystem syndrome" or "PIMS-TS" or "Kawa-COVID-19" or "MIS-C" or "multisystem inflammatory syndrome in children" or pediatric multisystem inflammatory disease).mp.
4. (or/1-3) and ((20191* or 202*).dp. or 20190101:20301231.(ep).) [this set is the sensitive/broad part of the search]
5. 4 not (SARS or SARS-CoV or MERS or MERS-CoV or Middle East respiratory syndrome or camel* or dromedar* or equine or coronary or coronal or covidence* or covidien or influenza virus or HIV or bovine or calves or TGEV or feline or porcine or BCoV or PED or PEDV or PDCoV or FIPV or FCoV or SADS-CoV or canine or CCov or zoonotic or avian influenza or H1N1 or H5N1 or H5N6 or IBV or murine corona*).mp. [line 5 removes SARS, MERS and veterinary noise from the sensitive/broad search results]
6. ((pneumonia or covid* or coronavirus* or corona virus* or ncov* or 2019-ncov or sars*).mp. or exp pneumonia/) and Wuhan.mp. [Early articles about the outbreak]
7. (2019-ncov or ncov19 or ncov-19 or 2019-novel CoV or sars-cov2 or sars-cov-2 or sarscov2 or sarscov-2 or SARS-2-nCoV or SARS-2-Cov or SARS-COV-19 or Sars-coronavirus2 or Sars-coronavirus-2 or SARS 2 coronavirus* or Severe Acute Respiratory Syndrome-CoV-2 or SARS-like coronavirus* or coronavirus-19 or covid19 or covid-19 or covid 2019 or ((novel or new or nouveau) adj2 (CoV or nCoV or covid or coronavirus* or corona virus or Pandemi*2)) or ((covid or covid19 or covid-19 or SARS-CoV-2) and pandemic*2) or (coronavirus* and pneumonia)).mp. [specific to Covid-19, Covid pneumonia, Covid pandemic]
8. (COVID-19 or SARS-CoV-2).rx,px,ox,rn. or (COVID-19 or COVID-19 serotherapy or ORF7b protein, SARS-CoV-2 or ORF6 protein, SARS-CoV-2 or ORF8 protein, SARS-CoV-2 or pediatric multisystem inflammatory disease, COVID-19 related or envelope protein, SARS-CoV-2 or ORF7a protein, SARS-CoV-2 or spike protein, SARS-CoV-2 or ORF3a protein, SARS-CoV-2 or COVID-19 drug treatment or severe acute respiratory syndrome coronavirus 2 or membrane protein, SARS-CoV-2 or ORF1ab polyprotein, SARS-CoV-2 or nucleocapsid protein, Coronavirus or COVID-19 vaccine or COVID-19 diagnostic testing).os,ps,rn,rs. [Relevant Suppl. Concepts listed in MeSH 2021 Browser]
9. 4 and (exp Vaccination/ or exp Vaccines/ or "vaccin*".rn,ox,px,rx. or vaccin*.mp. or exp antibodies/ or antibodies.mp. or ("AAVCOVID" or "Ad5-nCoV" or "AdCOVID" or "AdimrSC-2f" or "AG0301-COVID19" or "ARCT-021 OR “LUNAR-COV19" or "AZD1222" or "Bacillus Calmette-Guerin vaccine" or BCG or "bacTRL-Spike" or "BBIBP-CorV" or "BNT162" or "ChAd-SARS-CoV-2-S" or "CoronaVac" or "COVAX-19" or "Covaxin" or "CVnCoV" or "DelNS1-2019-nCoV-RBD-OPT1" or "EpiVacCorona" or "GRAd-COV2" or "GX-19" or "HaloVax" or "HDT-301" or "INO-4800" or "JNJ-78436735” OR “Ad26.COV2.S" or "LineaDNA" or "LNP-nCoVsaRNA" or "Mechanism" or "Mechanism" or "Mechanism" or "Mechanism" or "Mechanism" or "mRNA-1273" or "MRT5500" or "NVX-CoV2373" or "PittCoVacc" or "SCB-2019" or "Sputnik V" or "T-COVIDTM" or "UB-612" or "UQ-CSL V451" or "V590" or "V591" or "VIR-7831" or "VXA-CoV2-1" or "ZyCoV-D").mp. or (mRNA vaccine$ or messenger RNA vaccine$ or AstraZeneca$1 or Janssen$s or Moderna$1 or Novavax$1 or Pfizer$1 or BioNTech$1).mp.) [Line to add everything related to Vaccines and coronavirus]
10. 4 and (Chloroquine or hydroxychloroquine or convalescent plasma or Remdesivir or Veklury or azithromycin or bamlanivimab or "LY CoV555" or corticosteroids or glucocorticoids or "vitamin C" or lopinavir or ritonavir or ivermectin or Tocilizumab or Favipiravir or dexamethasone HIV protease inhibitors).mp. [specific to Covid specific drug treatment]
11.
("32185863" or "32172715" or "32227595" or "32140676" or "32246156" or "32267941" or "32176889" or "32169616" or "32265186" or "32253187" or "32152148" or "32053580" or "32179788" or "32213260" or "32205350" or "32188729" or "32152361" or "32277065" or "32088947" or "32240583" or "31917786" or "32127714" or "32047315" or "32020111" or "32240632" or "32243118" or "32267344" or "32239781" or "32396977" or "32402130" or "32243299" or "32807526" or "32344395" or "32403202" or "32389714" or "32416016" or "32405099" or "32976849" or "32685966" or "33221888" or "32379271" or "32188728" or "32221976" or "32417321" or "32489438" or "32332959" or "32943452" or "32807525" or "32826274" or "32898560" or "32293023" or "33159926" or "32919952" or "32835716" or "32619499" or "32663524" or "32392627" or "32392625" or "33037657" or "32777045" or "32521569" or "32492200" or "32930765" or "33075143" or "32237249" or "32683439" or "32495994" or "32344447" or "32896006" or "32240549" or "32438448" or "32425477" or "32951095" or "32274794" or "32750178" or "32463935" or "32428286" or "32491981" or "32930748" or "32119409" or "32432657" or "33003176" or "32459319" or "32822920" or "32878290" or "32270498" or "32250493" or "32512243" or "32837399" or "32426074" or "32199942" or "32839969" or "32639522" or "33073717" or "32502134" or "32334003" or "32510470" or "32819741" or "32309248" or "32243951" or "32378772" or "32835361" or "32962779" or "32916324" or "32785973" or "32272221" or "32299207" or "33044515" or "33134955" or "32970917" or "32407438" or "32513790" or "32439468" or "33063036" or "33077677" or "32406056" or "32716821" or "32588590" or "32239757" or "32829902" or "32807521" or "32379350" or "33125767" or "32829731" or "32988821" or "32780977" or "32648633" or "32829907" or "32330635" or "32692998" or "33013067" or "33010706" or "32502292" or "32780969" or "32998780" or "32754731" or "32639607" or "32233030" or "32953429" or "32246897" or "32955802" or "32425490" or "32418270" or "32445255" or "32775945" or "32775948" or "32775953" or "32407043").ui. [Selected Articles not captured by this hedge when updated on 1 December 2020]
12. or/5-11 [Lines 5 to 11 are specific/relevant to the Covid-19 outbreak]
13. 12 and 20191201:20301231.(dt). [only include records created for PubMed/MEDLINE from 1 December 2019 onwards]
1 exp Coronavirus/
2 exp Coronavirus Infections/
3 (coronavirus* or corona virus* or OC43 or NL63 or 229E or HKU1 or HCoV* or ncov* or covid* or sars-cov* or sarscov* or Sars-coronavirus* or Severe Acute Respiratory Syndrome Coronavirus*).mp.
4 (or/1-3) and ((20191* or 202*).dp. or 20190101:20301231.(ep).) [this set is the sensitive/broad part of the search]
5 4 not (SARS or SARS-CoV or MERS or MERS-CoV or Middle East respiratory syndrome or camel* or dromedar* or equine or coronary or coronal or covidence* or covidien or influenza virus or HIV or bovine or calves or TGEV or feline or porcine or BCoV or PED or PEDV or PDCoV or FIPV or FCoV or SADS-CoV or canine or CCov or zoonotic or avian influenza or H1N1 or H5N1 or H5N6 or IBV or murine corona*).mp. [line 5 removes noise in the search results]
6 ((pneumonia or covid* or coronavirus* or corona virus* or ncov* or 2019-ncov or sars*).mp. or exp pneumonia/) and Wuhan.mp.
7 (2019-ncov or ncov19 or ncov-19 or 2019-novel CoV or sars-cov2 or sars-cov-2 or sarscov2 or sarscov-2 or Sars-coronavirus2 or Sars-coronavirus-2 or SARS-like coronavirus* or coronavirus-19 or covid19 or covid-19 or covid 2019 or ((novel or new or nouveau) adj2 (CoV on nCoV or covid or coronavirus* or corona virus or Pandemi*2)) or ((covid or covid19 or covid-19) and pandemic*2) or (coronavirus* and pneumonia)).mp.
8 COVID-19.rx,px,ox. or severe acute respiratory syndrome coronavirus 2.os.
9 ("32240632" or "32236488" or "32268021" or "32267941" or "32169616" or "32267649" or "32267499" or "32267344" or "32248853" or "32246156" or "32243118" or "32240583" or "32237674" or "32234725" or "32173381" or "32227595" or "32185863" or "32221979" or "32213260" or "32205350" or "32202721" or "32197097" or "32196032" or "32188729" or "32176889" or "32088947" or "32277065" or "32273472" or "32273444" or "32145185" or "31917786" or "32267384" or "32265186" or "32253187" or "32265567" or "32231286" or "32105468" or "32179788" or "32152361" or "32152148" or "32140676" or "32053580" or "32029604" or "32127714" or "32047315" or "32020111" or "32267950" or "32249952" or "32172715").ui. [Articles not captured by this search when created in April 2020, pending further indexing by NLM]
10 or/6-9 [Lines 6 to 9 are specific to Covid-19]
11 5 or 10
12 (11 and 20191201:20301231.(dt).) use medall
13 (((pneumonia or covid* or coronavirus* or corona virus* or ncov* or 2019-ncov or sars*) adj5 Wuhan) or (SARS coronavirus* and Wuhan)).mp.
14 (2019-ncov or ncov19 or ncov-19 or 2019-novel CoV or sars-cov2 or sars-cov-2 or sarscov2 or sarscov-2 or Sars-coronavirus2 or Sars-coronavirus-2 or coronavirus-19 or covid19 or covid-19 or covid 2019 or "novel coronavirus" or "new coronavirus" or "nouveau coronavirus" or CoV or nCoV or covid or covid19 or covid-19 or "coronavirus 2" or ((novel or new or nouveau) adj1 (CoV or nCoV or covid or coronavirus* or "corona virus" or Pandemi*2)) or ((covid or covid19 or covid-19) and pandemic*2)).mp. [mp=ti, ab, ot, nm, hw, fx, kf, ox, px, rx, ui, sy, tx, ct]
15 (COVID-19 or "severe acute respiratory syndrome 2" or 2019 pandemic or 2020 pandemic).mp. or SARS-like coronavirus*.ti,ab,ct.
16 or/13-15
17 (16 and 2020:Current.(yr).) use ovft
18 12 or 17
19 Hydroxychloroquine/
20 Hydroxychloroquine.ti,ot,ab.
21 (hydroxychloroquine or Plaquenil or 118 42 3 or Oxichloroquine or Oxychlorochin or Oxychloroquine or Oxichlorochinum or Hidroxicloroquina or Hydroxychloroquinum or Hydroxychloroquine or "Idrossiclorochina DCIT" or oxichlorochine or Hidroxicloroquina or Hydroxychloroquinum or Quensyl or Hydroxychlorochin or Idrossiclorochina or Polirreumin or (HYDROXY adj1 CHLOROQUINE) or (WIN adj1 "1258")).mp.
22 (hydroxychloroquine or Plaquenil or 118 42 3 or Oxichloroquine or Oxychlorochin or Oxychloroquine or Oxichlorochinum or Hidroxicloroquina or Hydroxychloroquinum or Hydroxychloroquine or "Idrossiclorochina DCIT" or oxichlorochine or Hidroxicloroquina or Hydroxychloroquinum or Quensyl or Hydroxychlorochin or Idrossiclorochina or Polirreumin or (HYDROXY adj1 CHLOROQUINE) or (WIN adj1 "1258")).ti,ot,ab.
23 Chloroquine/
24 ((((Aralen or arechine or arequin or chingamin or chlorochin or chloroquine or chloroquine sulfate or chloroquine sulphate or khingamin or nivaquine or oe48649k6n or sulfate) adj1 chloroquine) or sulphate) adj1 chloroquine).mp.
25 ((((Aralen or arechine or arequin or chingamin or chlorochin or chloroquine or chloroquine sulfate or chloroquine sulphate or khingamin or nivaquine or oe48649k6n or sulfate) adj1 chloroquine) or sulphate) adj1 chloroquine).ti,ot,ab.
26 ("chingamin phosphate" or "unspecified phosphate of chloroquine diphosphate" or delagil or "khingamin phosphatez" or arechin or "chloroquine phosphate" or Resochin or "chloroquine diphosphate" or "chloroquine bis dihydrogenphosphate dihydrate" or "chloroquine diphosphate isomer").mp.
27 ("chingamin phosphate" or "unspecified phosphate of chloroquine diphosphate" or delagil or "khingamin phosphatez" or arechin or "chloroquine phosphate" or Resochin or "chloroquine diphosphate" or "chloroquine bis dihydrogenphosphate dihydrate" or "chloroquine diphosphate isomer").ti,ot,ab.
28 (6E17K3343P or 886U3H6UFF or 4QWG6N8QKH).rn. [SEARCH NOTE registry numbers for chloroquine diphosphate and hydroxychloroquine]
29 or/19-28
30 18 and 29
31 remove duplicates from 30
1 disease outbreaks/ or epidemics/ or pandemics/ or disease transmission, infectious/ or exp equipment contamination/ or equipment reuse/ or exp hygiene/ or exp Infection Control/ or exp coronavirus/ (214831)
2 ((disease$ adj2 outbreak$) or epidemic$ or pandemic$ or pandemie* or influenza or SARS or MERS or flu or tuberculosis or zika or ebola or covid19 or "covid-19" or "SARS-CoV-2" or "2019-nCov" or coronavirus* or corona-virus* or nCov or SARS-CoV*).mp. (546174)
3 middle east respiratory syndrome coronavirus/ or sars virus/ or exp Tuberculosis/ or influenza, Human/ or exp respiratory tract infections/ (466650)
4 or/1-3 (866741)
5 ((cloth$ or DIY or "do it yourself" or t-shirt$ or homemade or home-made or bandana$ or scarf$ or neckscarf$ or kerchief$ or napkin$ or bracup$ or bra-cup$ or 3D or "3-D" or cotton$ or muslin$ or gauze$ or "cheese cloth" or towel$ or fabric$ or tight$ woven or tight$ weav$) adj2 (facemask$ or face-mask$ or mask$)).mp. (299)
6 (((home adj1 made) or homemaker$ or household$ or "house hold$") adj1 mask$).mp. (3)
7 ("16752475" or "26980847" or "25903751" or "18612429" or "32203710" or "23968983" or "25903751" or "19702582" or "20584862").ui. (8)
8 or/5-7 (305)
9 (((cloth$ or DIY or "do it yourself" or t-shirt$ or homemade or home-made or bandana$ or scarf$ or neckscarf$ or kerchief$ or napkin$ or bracup$ or bra-cup$ or 3D or "3-D" or cotton$ or muslin$ or gauze$ or "cheese cloth" or towel$ or fabric$ or tight$ woven or tight$ weav$) adj (facemask$1 or face-mask$1 or mask$1)) and (develop$ adj1 countr$)).mp. (3)
10 ("16752475" or "26980847" or "25903751" or "18612429" or "32203710" or "23968983" or "25903751" or "19702582" or "20584862").ui. (8)
11 "20390479".ui. (1)
12 (4 and 8) or 7 or 9 (29)
13 12 not 11 (28)
1. (((pneumonia or covid* or coronavirus* or corona virus* or ncov* or 2019-ncov or sars*) adj5 Wuhan) or (SARS coronavirus* and Wuhan)).mp.
2. (2019-ncov or ncov19 or ncov-19 or 2019-novel CoV or sars-cov2 or sars-cov-2 or sarscov2 or sarscov-2 or Sars-coronavirus2 or Sars-coronavirus-2 or coronavirus-19 or covid19 or covid-19 or covid 2019 or "novel coronavirus" or "new coronavirus" or "nouveau coronavirus" or CoV or nCoV or covid or covid19 or covid-19 or "coronavirus 2" or ((novel or new or nouveau) adj1 (CoV or nCoV or covid or coronavirus* or "corona virus" or Pandemi*2)) or ((covid or covid19 or covid-19) and pandemic*2)).mp. [mp=title, abstract, full text, caption text]
3. (COVID-19 or "severe acute respiratory syndrome 2" or 2019 pandemic or 2020 pandemic).mp. or SARS-like coronavirus*.ti,ab,ct.
4. or/1-3
5. limit 4 to yr="2020 -Current"
6. remove duplicates from 5
1 exp Coronavirus/
2 exp Coronavirus Infections/
3 (coronavirus* or corona virus* or OC43 or NL63 or 229E or HKU1 or HCoV* or ncov* or covid* or sars-cov* or sarscov* or Sars-coronavirus* or Severe Acute Respiratory Syndrome Coronavirus*).mp.
4 (or/1-3) and ((20191* or 202*).dp. or 20190101:20301231.(ep).) [this set is the sensitive/broad part of the search]
5 4 not (SARS or SARS-CoV or MERS or MERS-CoV or Middle East respiratory syndrome or camel* or dromedar* or equine or coronary or coronal or covidence* or covidien or influenza virus or HIV or bovine or calves or TGEV or feline or porcine or BCoV or PED or PEDV or PDCoV or FIPV or FCoV or SADS-CoV or canine or CCov or zoonotic or avian influenza or H1N1 or H5N1 or H5N6 or IBV or murine corona*).mp. [line 5 removes noise in the search results]
6 ((pneumonia or covid* or coronavirus* or corona virus* or ncov* or 2019-ncov or sars*).mp. or exp pneumonia/) and Wuhan.mp.
7 (2019-ncov or ncov19 or ncov-19 or 2019-novel CoV or sars-cov2 or sars-cov-2 or sarscov2 or sarscov-2 or Sars-coronavirus2 or Sars-coronavirus-2 or SARS-like coronavirus* or coronavirus-19 or covid19 or covid-19 or covid 2019 or ((novel or new or nouveau) adj2 (CoV on nCoV or covid or coronavirus* or corona virus or Pandemi*2)) or ((covid or covid19 or covid-19) and pandemic*2) or (coronavirus* and pneumonia)).mp.
8 COVID-19.rx,px,ox. or severe acute respiratory syndrome coronavirus 2.os.
9 ("32240632" or "32236488" or "32268021" or "32267941" or "32169616" or "32267649" or "32267499" or "32267344" or "32248853" or "32246156" or "32243118" or "32240583" or "32237674" or "32234725" or "32173381" or "32227595" or "32185863" or "32221979" or "32213260" or "32205350" or "32202721" or "32197097" or "32196032" or "32188729" or "32176889" or "32088947" or "32277065" or "32273472" or "32273444" or "32145185" or "31917786" or "32267384" or "32265186" or "32253187" or "32265567" or "32231286" or "32105468" or "32179788" or "32152361" or "32152148" or "32140676" or "32053580" or "32029604" or "32127714" or "32047315" or "32020111" or "32267950" or "32249952" or "32172715").ui. [Articles not captured by this search when created in April 2020, pending further indexing by NLM]
10 or/6-9 [Lines 6 to 9 are specific to Covid-19]
11 5 or 10
12 (11 and 20191201:20301231.(dt).) use medall
13 (((pneumonia or covid* or coronavirus* or corona virus* or ncov* or 2019-ncov or sars*) adj5 Wuhan) or (SARS coronavirus* and Wuhan)).mp.
14 (2019-ncov or ncov19 or ncov-19 or 2019-novel CoV or sars-cov2 or sars-cov-2 or sarscov2 or sarscov-2 or Sars-coronavirus2 or Sars-coronavirus-2 or coronavirus-19 or covid19 or covid-19 or covid 2019 or "novel coronavirus" or "new coronavirus" or "nouveau coronavirus" or CoV or nCoV or covid or covid19 or covid-19 or "coronavirus 2" or ((novel or new or nouveau) adj1 (CoV or nCoV or covid or coronavirus* or "corona virus" or Pandemi*2)) or ((covid or covid19 or covid-19) and pandemic*2)).mp. [mp=ti, ab, ot, nm, hw, fx, kf, ox, px, rx, ui, sy, tx, ct]
15 (COVID-19 or "severe acute respiratory syndrome 2" or 2019 pandemic or 2020 pandemic).mp. or SARS-like coronavirus*.ti,ab,ct.
16 or/13-15
17 (16 and 2020:Current.(yr).) use ovft
18 12 or 17
19 exp "Protective Clothing"/ or gown*.mp. or coverall*.mp. or "protective layer".mp. or "protective layers".mp. or "surgical toga".mp. or apron*.mp. or "smock".mp. or "smocks".mp. or "hazmat suit".mp. or (hazmat and suit).mp. or exp "Gloves, Protective"/ or "glove".mp. or "gloves".mp. or "Respiratory Protective Devices"/ or "Masks"/ or "mask".mp. or "masks".mp. or "N95".mp. or "air-purifying respirator".mp. or "PAPR".mp. or "enhanced respiratory and contact precautions".mp. or "respiratory protection".mp. or "transparent panel".mp. or "surgical mask".mp. or "surgical masks".mp. or "filtering face piece".mp. or "filtering facepiece".mp. or "Eye Protective Devices"/ or goggle*.mp. or "visor".mp. or "facial protection equipment".mp. or "safety glass".mp. or "safety glasses".mp. or "safety spectacles".mp. or "personal protective equipment".mp. or "PPE".mp. or "protective equipment".mp. or overshoe*.mp. or "shoe cover".mp. or "shoe covers".mp. or "rubber boot".mp. or "rubber boots".mp. or "head cover".mp. or "head covering".mp. or "face shield".mp. or "face shields".mp. or "surgical hood".mp. or "hood".mp. or exp Equipment Contamination/pc or exp "Infection Control"/ or "infection control".ti,ab. or "gloving".mp. or "donning".mp. or "doffing".mp.
20 ((("Protective Cloth$3" or gown* or coverall* or "protective layer$1" or "surgical toga" or apron* or "smock" or "smocks" or "hazmat suit" or (hazmat and suit) or PPE or glove$3 or Respiratory Protective Device$ or "Mask$1 or N95 or air-purifying respirator or PAPR or enhanced respiratory") and "contact precautions or respiratory protection or transparent panel or surgical mask or surgical mask$1 or filtering face piece or filtering facepiece or Eye Protective Devices or goggle* or visor or facial protection equipment or safety glass or safety glasses or safety spectacles or personal protective equipment or PPE or protective equipment or overshoe* or shoe cover$1 or rubber boot$1 or head cover$5 or face shield$3 or ace shield$1") or "surgical hood" or "hood" or Contamination equipment or decontamination equipment or "Infection Control" or "gloving" or "donning" or "doffing").ti,ot,ab,kw.
21 18 and (19 or 20)
22 remove duplicates from 21
1 disease outbreaks/ or epidemics/ or pandemics/ or exp coronavirus/ or Severe Acute Respiratory Syndrome/ or middle east respiratory syndrome coronavirus/ or sars virus/ or exp Tuberculosis/ or influenza, Human/ or exp respiratory tract infections/ (545736)
2 ((disease$ adj2 outbreak$) or epidemic$ or pandemic$ or pandemie* or influenza or SARS or MERS or flu or tuberculosis or zika or ebola or covid19 or "covid-19" or "SARS-CoV-2" or "2019-nCov" or coronavirus* or corona-virus* or nCov or SARS-CoV*).mp. (546621)
3 or/1-2 (761927)
4 Stress, Psychological/pc and Nurses/px (171)
5 *nurses/px or exp *nursing staff/px or nurs$.ti. (266930)
6 adaption, psychological/ or mindfulness/ or relaxation therapy/mt or virtual reality exposure therapy/ or mind-body relations, metaphysical/ or burnout, professional/pc or stress, psychological/pc or exp Mental Fatigue/pc or Resilience, Psychological/ (22349)
7 ("27706912" or "27271136" or "26982825" or "26778081" or "26755462" or "26665843" or "26414585" or "26414566" or "25703040" or "25141425" or "25004803" or "24771664" or "24020546").ui. (13)
8 4 or 7 or (5 and 6) [Search NOTE nursing as major concept and stress coping terms] (2667)
9 3 and 8 [Search NOTE nursing as major concept and stress coping and disease outbreaks] (9)
10 limit 8 to yr="2015 -Current" (525)
11 9 or 10 [Search NOTE nursing stress coping with or without pandemic] (532)
1. ((*Burns/ or burns, inhalation/ or smoke inhalation injury/ or wildfire$.mp. or bushfire$.mp. or burn$.mp.) not sunburn/) and ((exp emergency responders/ or emergency responder$.mp. or relief work/ or relief work$.mp. or rescue work/ or rescue work$.mp. or recovery worker$.mp.) and (exp safety/ or safety.mp. or occupational exposure/))
2. limit 1 to yr="2010 -Current"
1. (((*burns/ or burns, inhalation/ or smoke inhalation injury/ or wildfire$.mp. or wildfires/ or burn$.mp.) and (mass casualty incidents/ or disaster$.mp. or disasters/ or emergency medical services/)) not sunburn/) and (mental health/ or mental health.mp. or (stress disorders, post-traumatic/ or posttraumatic.mp. or post traumatic.mp. or resilience, psychological/ or stress, psychological/ or stress.mp. or adaption, psychological/ or psychological adaption.mp. or coping.mp.) or mental disorders/)
2. limit 1 to (english language and yr="2010 -Current")
1. (exp Australia/ and ((*burns/ or burns, inhalation/ or smoke inhalation injury/ or wildfire$.mp. or wildfires/ or burn$.mp.) and (mass casualty incidents/ or disaster$.mp. or disasters/ or emergency medical services/ or civil defense/ or public health/ or (cleanup$ or "recovery adj2 manag$").mp.))) or (exp Australia/ and ((*burns/ or burns, inhalation/ or smoke inhalation injury/ or wildfire$.mp. or wildfires/ or burn$.mp.) and (exp emergency responders/ or emergency responder$.mp. or relief work/ or relief work$.mp. or rescue work/ or rescue work$.mp. or recovery worker$.mp.)))
2. limit 1 to (english language and yr="2010 -Current")
1. wildfire$.mp. or wildfires/ or *burns/ or burns, inhalation/ or smoke inhalation injury/ or smoke/ or soot/
2 . exp marsupialia/ or exp reptiles/ or exp birds/ or kangaroo$.mp. or wallaby$.mp. or wallaroo$.mp. or pademelon$.mp. or quokka$.mp. or phalangeriform$.mp. or opossum$.mp. or wombat$.mp. or reptile$.mp. or bird$.mp.
3. exp galliformes/ or chickens/ or poultry/ or livestock/ or broiler$1.mp. or chicken$1.mp. or rarely burned.mp. or frack$.mp. or ancient.mp.
4. (1 and 2) NOT 3
5. limit 4 to (english language and yr="2010 -Current")
1 . exp burns/
2. (fire$ or wildfire$ or brushfire$ or brush fire$).mp.
3. limit 2 to (burns care or "emergency and trauma" or "health management and assessment" or infection control or mental health or surgical services or "wound healing and management")
4. 1 or 3
5. (Hydrofluoric Acid or Electrosurgery or oxygen or MRI or burn prevention or prevent burn).mp. 6. 4 not 5
Middle East Respiratory Syndrome Coronavirus/ or (middle east* respirator* or (mers* and respirator*)).mp
coronavirus/ and ((middle east* or mid east*).ti,ab. or exp korea/)
(Novel coronavirus or nCoV).ti,ab. and ((middle east* or mid east*).ti,ab. or exp korea/)
((mers adj4 virus*) or (cov adj4 mers) or (Middle east respiratory syndrome coronavirus or MERS-CoV)).ti,ab.
1 or 2 or 3 or 4
(merseburg or mersalyl).mp.
5 not 6
Middle East Respiratory Syndrome Coronavirus/ or (middle east* respirator* or (mers* and respirator*)).mp.
coronavirus/ and ((middle east* or mid east*).ti,ab. or exp korea/)
(Novel coronavirus or nCoV).ti,ab. and ((middle east* or mid east*).ti,ab. or exp korea/)
((mers adj4 virus*) or (cov adj4 mers) or (Middle east respiratory syndrome coronavirus or MERS-CoV)).ti,ab.
1 or 2 or 3 or 4
(merseburg or mersalyl).mp.
5 not 6
1. exp Earthquakes/ or (earthquake$ or aftershock$).ti,kw.
2. exp "diseases (non mesh)"/ or disease/ or exp parasites/ or exp
bacteria/ or exp viruses/ or (infection$ or disease$ or virus$ or
viral$ or bacteria$ or bacterium$ or pathogen$ or parasit$).ti,kw.
3. exp "Wounds and Injuries"/ or (wound$1 or injur$).ti,kw.
4. exp Emergency Medical Services/
5. 1 and (2 or 3 or 4)
1. exp Volcanic Eruptions/
2. exp "diseases (non mesh)"/ or disease/ or exp parasites/ or exp bacteria/ or exp viruses/ or "Wounds and Injuries"/ or exp Emergency Medical Services/ or disaster planning/
3. disasters/ and (gas poisoning/ or dust/) and volcano$.mp.
4. (1 and 2) or 3
5. limit 4 to humans
(ptsd or pts or psych$ or post trauma$ or posttrauma$ or (stress$ and (mental or chronic or trauma$ or disease$ or patient$))).mp. or (exp "behavior and behavior mechanisms"/ or exp "psychological phenomena"/ or exp mental disorders/ or stress disorders, post-traumatic/)
exp Earthquakes/ or (earthquake$ or aftershock$).ti,kw.
1 and 2
1. review.pt.
2. review literature as topic/
3. review.af.
4. 1 or 2 or 3
5. exp hemorrhagic fever, ebola/ or exp ebolavirus/
6. ebola.af.
7. virus$2.mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier]
8. (ebola virus or ebolavirus).af.
9. 6 and 7
10. 5 or 8 or 9
11. 4 and 10
enterovirus 68.mp.
Enterovirus D.mp.
Enterovirus D68.mp.
EV-D68.mp.
ev68.mp.
(pediatric$1 or paediatric$1 or child or children$1 or kid$ or bab$3 or infant$ or newborn$ or preschool$ or toddler$1).mp.
(1 or 2 or 3 or 4 or 5) and 6
exp paralysis/
exp Respiratory Tract Infections/
*Enterovirus Infections/
*Enterovirus D, Human/
*Enterovirus/
8 or 9
13 and (10 or 11 or 12)
limit 14 to "all child (0 to 18 years)"
7 or 15
Sepsis or Systemic Inflammatory Response Syndrome With Clinical Filter to Maximize Specificity for Therapy - last 3 years, humans
(sepsis or Systemic Inflammatory Response Syndrome or SIRS).ti. and (in process or in data review).st.
exp *sepsis/ or exp *systemic inflammatory response syndrome/
limit 1 to "therapy (maximizes sensitivity)"
3 not (dog$ or cat$ or rat$ or mice or mouse).mp.
limit 2 to (humans and "therapy (maximizes specificity)")
5 not animals/
4 or 6
limit 7 to last 3 years
Sepsis or Systemic Inflammatory Response Syndrome With Clinical Filter to Maximize Specificity for Therapy - last 3 years, humans
(sepsis or Systemic Inflammatory Response Syndrome or SIRS).ti. and (in process or in data review).st
exp *sepsis/ or exp *systemic inflammatory response syndrome/
limit 1 to ("diagnosis (maximizes specificity)" and last 3 years)
limit 2 to (humans and "diagnosis (maximizes specificity)" and last 3 years)
3 or 4
5 not (animals/ or mice.mp. or mouse.mp. or cat$.mp. or dog$.mp. or rat$.mp.)
For Sepsis or Systemic Inflammatory Response Syndrome
exp *sepsis/ or
exp *systemic inflammatory response syndrome/
(sepsis or Systemic Inflammatory Response Syndrome or SIRS).ti. and (in process or in data review).st. and (bundle$ or guideline$).mp.
2 not (dog$ or cat$ or rat$ or mice or mouse).mp.
(bundle$1 or guideline$1).ti,ab. or exp guideline/ or Consensus Development Conference.pt.
1 and 4
limit 5 to humans
6 not animals/
2 or 7
Sepsis or Systemic Inflammatory Response Syndrome For the healthcare professional or the patient last 5 years
(sepsis or Systemic Inflammatory Response Syndrome or SIRS).ti. and (in process or in data review).st.
exp *sepsis/ or exp *systemic inflammatory response syndrome/
exp health education/ or exp education/
((prof$ adj1 educat$) or (prof adj1 develop$) or (continuing adj1 educat$) or (continuing adj1 med$ adj1 educat$)).ti,ab.
(CME or CE).ti,ab.
(educat$ or ((health$ adj1 educat$) or (consumer$ adj1 health) or (patient$ adj1 educat$))).ti,ab.
(1 and (4 or 5 or 6)) or (2 and 3)
exp schools/
7 not 8
Of Sepsis or Systemic Inflammatory Response Syndrome Human last 5 years
exp *sepsis/ or exp *systemic inflammatory response syndrome/
sepsis/px or inflammatory response syndrome/px
exp behavioral symptoms/ or exp child behavior/ or cognition disorders/ or depression/ or activities of daily living/px or quality of life/px or survivors/px
((sepsis or Systemic Inflammatory Response Syndrome or SIRS).ti. and (in process or in data review).st. and (depression$1 or cogniti$ or behavior$).ti,ab.) not (dog$ or cat$ or rat$ or mice or mouse).mp.
(1 and 3) or 2
limit 5 to humans
6 not animals/
7 or 4
limit 8 to last 5 years
health litera$2.af.
medical literacy.af.
(health and literacy).ti.
(functional and health and literacy).tw.
low-litera$2.ti.
litera$2.ti.
illitera$2.ti.
reading/
comprehension/
*health promotion/
*health education/
*patient education/
*communication barriers/
*communication/
*health knowledge,attitudes,practice/
*attitude to health/
*comprehension/ and *educational status/
(family and literacy).ti.
(drug labeling.af. or prescriptions, drug/) and comprehension.af.
((cancer or diabetes or genetics) and (literacy or comprehension)).ti.
(adult and (educational status or (educational and status) or literacy)).af.
(limited and (educational status or (educational and status) or literacy)).af.
(patient$1 and (educational status or (educational and status) or literacy)).af.
(patient$1 and (comprehension or understanding)).ti.
or/1-9
or/10-24
25 and 26
limit 27 to english language
delivery of health care/
Health Behavior/
Health Knowledge, Attitudes, Practice/
Health Services Accessibility/
health services, indigenous/
mass screening/
mass screening$.ti,ab.
health inequalit$.ti,ab.
health inequit$.ti,ab.
"Health Services Needs and Demand"/
"Patient Acceptance of Health Care"/
patient selection/
*quality of health care/
quality of life/
quality of life.ti,ab.
social disparit$.ti,ab.
social inequit$.ti,ab.
*socioeconomic factors/
socioeconomic factor$1.ti,ab.
or/1-19
African Americans/
african american$.ti,ab.
african ancestry.ti,ab.
African Continental Ancestry Group/
aian.ti,ab.
American Native Continental Ancestry Group/
Asian Continental Ancestry Group/
asian$1.ti,ab.
black$1.ti,ab.
caucasian$1.ti,ab.
diverse population$1.ti,ab.
environmental justice.ti,ab.
ethnic group$1.ti,ab.
Ethnic Groups/
ethnic population$1.ti,ab.
ghetto$1.ti,ab.
hispanic$1.ti,ab.
indian$1.ti,ab.
latino$1.ti,ab.
latina$1.ti,ab.
Medically Underserved Area/
minority group$1.ti,ab.
minority population$1.ti,ab.
Minority Groups/
native american$1.ti,ab.
oceanic ancestry group/
pacific islander$1.ti,ab.
people of color.ti,ab.
poverty area/
poverty area$1.ti,ab.
rural health/
rural health.ti,ab.
rural health services/
rural population/
rural population$1.ti,ab.
slum$1.ti,ab.
urban health/
urban health services/
urban population/
urban population$1.ti,ab.
vulnerable populations/
vulnerable population$1.ti,ab.
white.ti,ab.
whites.ti,ab.
or/21-64
ethnic disparit$3.ti,ab.
health care disparit$3.ti,ab.
health disparit$3.ti,ab.
health status disparities/
healthcare disparit$3.ti,ab.
healthcare disparity/
minority health/
minority health.ti,ab.
racial disparit$3.ti,ab.
racial equality.ti,ab.
racial equity.ti,ab.
racial inequit$3.ti,ab.
or/66-77
20 and (65 or 78)
random$.ti,ab.
exp epidemiologic studies/
odds ratio/
cohort$.ti,ab.
(case$1 adj control$).ti,ab.
risk$.ti,ab.
(odds adj ratio$1).ti,ab.
causa$.ti,ab.
(relative$1 adj risk$).ti,ab.
predispos$.ti,ab.
(randomized controlled trial or controlled clinical trial).pt.
exp risk/
practice guideline.pt.
case-control studies/
or/1-14
exp "sensitivity and specificity"/
false negative reactions/ or false positive reactions/
(sensitivity or specificity).ti,ab.
(predicitve adj value$1).ti,ab.
(likelihood adj ratio$1).ti,ab.
(false adj (negative$1 or positive$1)).ti,ab.
(randomized controlled trial or controlled clinical trial).pt
double blind method/ or single blind method/
practice guideline.pt
consensus development conference.pt
random$.ti,ab.
random allocation/
(single blind$3 or double blind$3 or triple blind$3).ti,ab.
(review or review academic).pt
meta analysis.pt
(systematic adj review$).ti,ab.
or/1-14
17 and (15 or 16)
exp research design/
exp clinical trial/
comparative study/ or placebos/
multicenter study.pt.
clinical trial$1.pt.
random$.ti,ab.
(double blind$ or triple blind$3).ti,ab.
placebo$.ti,ab.
(clinical adj trial$1).ti,ab.
exp epidemiologic research design/
(controlled clinical trial or randomized controlled trial).pt.
practice guideline.pt.
feasibility studies/
clinical protocols/
exp treatment outcome/
or/1-15
exp "sensitivity and specificity"/
false negative reactions/ or false positive reactions/
(sensitivity or specificity).ti,ab.
(predictive adj value$1).ti,ab.
(likelihood adj ratio$1).ti,ab.
(false adj (negative$1 or positive$1)).ti,ab.
(randomized controlled trial or controlled clinical trial).pt.
double blind method/ or single blind method/
practice guideline.pt.
consensus development conference$.pt.
random$.ti,ab.
random allocation/
(single blind$3 or double blind$3 or triple blind$3).ti,ab.
or/1-13
Randomized controlled trials as Topic/
Randomized controlled trial/
Random allocation/
Double blind method/
Single blind method/
Clinical trial/
Exp Clinical Trials as Topic/
Or/1-7
(clinic$ adj trial$1).tw.
((singl$ or doubl$ or treb$ or tripl$) adj (blind$3 or mask$3)).tw.
Placebos/
Placebo$.tw.
Randomly allocated.tw.
(allocated adj2 random).tw.
Or/9-14
8 or 15
Case report.tw.
Letter/
Historical article/
Review of reported cases.pt.
Review, multicase.pt.
Or/17-21
16 not 22
Epidemiologic studies/
Exp case control studies/
Exp cohort studies/
Case control.tw.
(cohort adj (study or studies)).tw.
Cohort analy$.tw.
(Follow up adj (study or studies)).tw.
(observational adj (study or studies)).tw.
Longitudinal.tw.
Retrospective.tw.
Cross sectional.tw.
Cross-sectional studies/
Or/1-12
exp adolescent/ or exp child/ or exp infant/ or (infant disease* or childhood disease*).ti,ab,kf. or (adolescen* or babies or baby or boy? or boyfriend or boyhood or girlfriend or girlhood or child* or girl? or infan* or juvenil* or kid? or minors or minors* or neonat* or neo-nat* or newborn* or new-born* or paediatric* or peadiatric* or pediatric* or perinat* or preschool* or puber* or pubescen* or school* or teen* or toddler? or underage? or under-age? or youth*).ti,ab,kf. or (pediatric* or paediatric* or infan* or child* or adolescen* or young).jn,jw or (pediatric* or paediatric* or infan* or child* or adolescen* or young).in
exp *adolescent/ or exp *child/ or exp *infant/ or (infant disease* or childhood disease*).ti,kf. or (adolescen* or babies or baby or boy? or boyfriend or boyhood or girlfriend or girlhood or child* or girl? or infan* or juvenil* or kid? or minors or minors* or neonat* or neo-nat* or newborn* or new-born* or paediatric* or peadiatric* or pediatric* or perinat* or preschool* or puber* or pubescen* or school* or teen* or toddler? or underage? or under-age? or youth*).ti,kf. or (pediatric* or paediatric* or infan* or child* or adolescen* or young).jn,jw or (pediatric* or paediatric* or infan* or child* or adolescen* or young).in
exp aged/ or exp geriatrics/ or exp geriatric nursing/ or (centarian* or centenarian* or elder* or eldest or frail* or geriatri* or nonagenarian* or octagenarian* or octogenarian* or old age* or older adult* or older age* or older female* or older male* or older man or older men or older patient* or older people or older person* or older population or older subject* or older woman or older women or oldest old* or senior* or senium or septuagenarian* or supercentenarian* or very old*).ti,ab,kf.
exp *aged/ or exp *geriatrics/ or exp *geriatric nursing/ or (centarian* or centenarian* or elder* or eldest or frail* or geriatri* or nonagenarian* or octagenarian* or octogenarian* or old age* or older adult* or older age* or older female* or older male* or older man or older men or older patient* or older people or older person* or older population or older subject* or older woman or older women or oldest old* or senior* or senium or septuagenarian* or supercentenarian* or very old*).ti,kf.
exp Pregnancy/ or exp Pregnancy Complications/ or exp Obstetrics/ or exp Breast Feeding/ or exp Prenatal Education/ or exp Labor Pain/ or (breast-feeding education or parturition or ante natal antenatal* or pre natal* or prenatal* or puerper* or postnatal* or postpartum or post partum or post natal* or peripartum or peri partum or prepregnancy or pre pregnancy or preconception* or pre conception* or periconception* or peri conception* or ((preterm or premature) and (labor or labour)) or eclamp* or preeclamp* or pre eclamp* or amniocentes* or chorion* vill* or breastfe* or breast fe* or lactation* or cesarean or caesarean or cesarian or caesarian or cesarien or caesarien or newborn* or new born* or tocoly* or fetal or foetal or fetus or foetus or miscarriage* or pregnancy or pregnancies or pregnant).ti,ab,kf
exp *Pregnancy/ or exp *Pregnancy Complications/ or exp *Obstetrics/ or exp *Breast Feeding/ or exp *Prenatal Education/ or exp *Labor Pain/ or (breast-feeding education or parturition or ante natal antenatal* or pre natal* or prenatal* or puerper* or postnatal* or postpartum or post partum or post natal* or peripartum or peri partum or prepregnancy or pre pregnancy or preconception* or pre conception* or periconception* or peri conception* or ((preterm or premature) and (labor or labour)) or eclamp* or preeclamp* or pre eclamp* or amniocentes* or chorion* vill* or breastfe* or breast fe* or lactation* or cesarean or caesarean or cesarian or caesarian or cesarien or caesarien or newborn* or new born* or tocoly* or fetal or foetal or fetus or foetus or miscarriage* or pregnancy or pregnancies or pregnant).ti,kf.
Economics/
"costs and cost analysis"/
Cost allocation/
Cost-benefit analysis/
Cost control/
Cost savings/
Cost of illness/
Cost sharing/
"deductibles and coinsurance"/
Medical savings accounts/
Health care costs/
Direct service costs/
Drug costs/
Employer health costs/
Hospital costs/
Health expenditures/
Capital expenditures/
Value of life/
Exp economics, hospital/
Exp economics, medical/
Economics, nursing/
Economics, pharmaceutical/
Exp "fees and charges"/
Exp budgets/
(low adj cost).mp.
(high adj cost).mp.
(health?care adj cost$).mp.
(fiscal or funding or financial or finance).tw.
(cost adj estimate$).mp.
(cost adj variable).mp.
(unit adj cost$).mp.
(economic$ or pharmacoeconomic$ or price$ or pricing).tw.
Or/1-32
1. (systematic review.ti. OR meta-analysis.pt. OR meta-analysis.ti. OR systematic literature review.ti. OR this systematic review.tw,kf,hw. OR pooling project.tw,kf,hw. OR (systematic review.ti,ab. AND review.pt.) OR meta synthesis.ti. OR meta-analy*.ti. OR integrative review.tw,kf,hw. OR integrative research review.tw,kf,hw. OR rapid review.tw,kf,hw. OR umbrella review.tw,kf,hw. OR consensus development conference.pt. OR practice guideline.pt. OR drug class reviews.ti. OR (1469-493X OR 1361-6137).is. OR (1539-8560 OR 1056-8751).is. OR (2046-4924 OR 1366-5278).is. OR 1530-440X.is. OR 2202-4433.is.)
2. (clinical guideline.tw,kf,hw. AND management.tw,kf,hw.) OR ((evidence based.ti. OR exp evidence-based medicine/ OR best practice*.ti. OR evidence synthesis.ti,ab.) AND (review.pt. OR exp diseases non mesh/ OR exp "behavior and behavior mechanisms"/ OR exp therapeutics/ OR evaluation studies.pt. OR validation studies.pt. OR guideline.pt. OR pmcbook.af.))
3. (systematic.tw,kf,hw. OR systematically.tw,kf,hw. OR critical.ti,ab. OR (study selection.tw,kf,hw.) OR (predetermined.tw,kf,hw. OR inclusion.tw,kf,hw. AND criteri*.tw,kf,hw.) OR exclusion criteri*.tw,kf,hw. OR main outcome measures.tw,kf,hw. OR standard of care.tw,kf,hw. OR standards of care.tw,kf,hw.)
4. (survey.ti,ab. OR surveys.ti,ab. OR overview*.tw,kf,hw. OR review.ti,ab. OR reviews.ti,ab. OR search*.tw,kf,hw. OR handsearch.tw,kf,hw. OR analysis.ti. OR critique.ti,ab. OR appraisal.tw,kf,hw. OR (reduction.tw,kf,hw. AND (exp risk/ OR risk.tw,kf,hw.) AND ((exp "death"/ OR "death".af.) OR (exp "recurrence"/ OR "recurrence".af.))))
5. (literature.ti,ab. OR articles.ti,ab. OR publications.ti,ab. OR publication.ti,ab. OR bibliography.ti,ab. OR bibliographies.ti,ab. OR published.ti,ab. OR pooled data.tw,kf,hw. OR unpublished.tw,kf,hw. OR citation.tw,kf,hw. OR citations.tw,kf,hw. OR database.ti,ab. OR internet.ti,ab. OR textbooks.ti,ab. OR references.tw,kf,hw. OR scales.tw,kf,hw. OR papers.tw,kf,hw. OR datasets.tw,kf,hw. OR trials.ti,ab. OR meta-analy*.tw,kf,hw. OR (clinical.ti,ab. AND studies.ti,ab.) OR exp treatment outcome/ OR treatment outcome.tw,kf,hw. OR pmcbook.af.)
6. (letter.pt. OR newspaper article.pt.)
7. 1 or 2
8. 3 and 4 and 5
9. 7 or 8
10. 9 not 6
sex factors
women's health/
women's health services/
exp women/
sex characteristics/
sex distribution/
sex determination.kf
gender identity/
journal of the american medical women's association.jn.
women & health.jn.
womens health issues.jn.
health care for women international.jn.
gender$.tw.
women$.tw.
woman$.tw.
female$.tw.
girl$.tw.
mother$.tw.
widow$.tw.
exp Meta Analysis/
((meta adj analy$) or metaanalys$).tw.
(systematic adj (review$1 or overview$1)).tw.
or/1-3
cancerlit.ab.
cochrane.ab.
embase.ab.
(psychlit or psyclit).ab.
(psychinfo or psycinfo).ab.
(cinahl or cinhal).ab.
science citation index.ab.
bids.ab.
or/5-12
reference lists.ab.
bibliograph$.ab.
hand-search$.ab.
manual search$.ab.
relevant journals.ab.
or/14-18
data extraction.ab.
selection criteria.ab.
20 or 21
review.pt.
22 and 23
letter.pt.
editorial.pt.
animal/
human/
27 not (27 and 28)
or/25-26,29
4 or 13 or 19 or 24
31 not 30
Clinical trial/
Randomized controlled trial/
Randomization/
Single blind procedure/
Double blind procedure/
Crossover procedure/
Placebo/
Randomi?ed controlled trial$.tw.
Rct.tw.
Random allocation.tw.
Randomly allocated.tw.
Allocated randomly.tw.
(allocated adj2 random).tw.
Single blind$.tw.
Double blind$.tw.
((treble or triple) adj (blind$)).tw.
Placebo$.tw.
Prospective study/
Or/1-18
Case study/
Case report.tw.
Abstract report/ or letter/
Or/20-22
19 not 23
Clinical study/
Case control study
Family study/
Longitudinal study/
Retrospective study/
Prospective study/
Randomized controlled trials/
6 not 7
Cohort analysis/
(Cohort adj (study or studies)).mp.
(Case control adj (study or studies)).tw.
(follow up adj (study or studies)).tw.
(observational adj (study or studies)).tw.
(epidemiologic$ adj (study or studies)).tw.
(cross sectional adj (study or studies)).tw
or/1-5,8-15
exp adolescence/ or exp adolescent/ or exp child/ or exp childhood disease/ or exp infant disease/ or (adolescen* or babies or baby or boy? or boyfriend or boyhood or girlfriend or girlhood or child* or girl? or infan* or juvenil* or juvenile* or kid? or minors or minors* or neonat* or neo-nat* or neo-nat* or newborn* or new-born* or paediatric* or peadiatric* or pediatric* or perinat* or preschool* or puber* or pubescen* or school or school child* or school* or schoolchild* or schoolchild* or (pediatric* or paediatric* or infan* or child* or adolescen* or young).jn,jw or (pediatric* or paediatric* or infan* or child* or adolescen* or young).in or teen* or toddler? or underage? or under-age? or youth*).ti,ab,kw
exp *adolescence/ or exp *adolescent/ or exp *child/ or exp *childhood disease/ or exp *infant disease/ or (adolescen* or babies or baby or boy? or boyfriend or boyhood or girlfriend or girlhood or child or child* or child*3 or children* or girl? or infan* or juvenil* or juvenile* or kid? or minors or minors* or neonat* or neo-nat* or newborn* or new-born* or paediatric* or peadiatric* or pediatric* or perinat* or preschool* or puber* or pubescen* or school* or teen* or toddler? or underage? or under-age? or youth*).ti,kw.
exp aged/ or exp geriatrics/ or exp elderly care/ or (centarian* or centenarian* or elder* or eldest or frail* or geriatri* or nonagenarian* or octagenarian* or octogenarian* or old age* or older adult* or older age* or older female* or older male* or older man or older men or older patient* or older people or older person* or older population or older subject* or older woman or older women or oldest old* or senior* or senium or septuagenarian* or supercentenarian* or very old*).ti,ab,kw.
exp *aged/ or exp *geriatrics/ or exp *elderly care/ or (centarian* or centenarian* or elder* or eldest or frail* or geriatri* or nonagenarian* or octagenarian* or octogenarian* or old age* or older adult* or older age* or older female* or older male* or older man or older men or older patient* or older people or older person* or older population or older subject* or older woman or older women or oldest old* or senior* or senium or septuagenarian* or supercentenarian* or very old*).ti,kw.
exp PREGNANCY/ or exp PREGNANCY DISORDER/ or exp OBSTETRIC PROCEDURE/ or exp BREAST FEEDING/ or exp BREAST FEEDING EDUCATION/ or exp BIRTH/ or exp CHILDBIRTH/ or CHILDBIRTH EDUCATION/ or LABOR PAIN/ or (ante natal or antenatal* or pre natal* or prenatal* or puerper* or postnatal* or postpartum or post partum or post natal* or peripartum or peri partum or prepregnancy or pre pregnancy or preconception* or pre conception* or periconception* or peri conception* or ((preterm or premature) and (labor or labour)) or eclamp* or preeclamp* or pre eclamp* or amniocentes* or chorion* vill* or breastfe* or breast fe* or lactation* or cesarean or caesarean or cesarian or caesarian or cesarien or caesarien or newborn* or new born* or tocoly* or fetal or foetal or fetus or foetus or miscarriage*).ti,ab,kw. or (pregnancy or pregnancies or pregnant).ti,kw.
exp PREGNANCY/ or exp PREGNANCY DISORDER/ or exp OBSTETRIC PROCEDURE/ or exp BREAST FEEDING/ or exp BREAST FEEDING EDUCATION/ or exp BIRTH/ or exp CHILDBIRTH/ or CHILDBIRTH EDUCATION/ or LABOR PAIN/ or (ante natal or antenatal* or pre natal* or prenatal* or puerper* or postnatal* or postpartum or post partum or post natal* or peripartum or peri partum or prepregnancy or pre pregnancy or preconception* or pre conception* or periconception* or peri conception* or ((preterm or premature) and (labor or labour)) or eclamp* or preeclamp* or pre eclamp* or amniocentes* or chorion* vill* or breastfe* or breast fe* or lactation* or cesarean or caesarean or cesarian or caesarian or cesarien or caesarien or newborn* or new born* or tocoly* or fetal or foetal or fetus or foetus or miscarriage*).ti,ab,kw. or (pregnancy or pregnancies or pregnant).ti,kw.
Socioeconomics/
Cost benefit analysis/
Cost effectiveness analysis/
Cost of illness/
Cost control/
Economic aspect/
Financial management/
Health care cost/
Health care financing/
Health economics/
Hospital cost/
(fiscal or financial or finance or funding).tw.
Cost minimization analysis/
(cost adj estimate$).mp.
(cost adj variable$).mp.
(unit adj cost$).mp.
Or/1-16
exp "drug-related side effects and adverse reactions"/or adverse.ti,ab, kf. or side effect?.ti,ab,kf. or adverse effects.fs. or exp drug overdose/ or overdos*.ti,ab,kf. or exp drug misuse/ or misus*.ti,ab,kf. or exp substance-related disorders/ or abus*.ti,ab,kf. or exp pregnancy/ or pregnan*.ti,ab,kf. or exp pregnancy complications/ or exp lactation/ or exp lactation disorders/ or exp breast feeding/ or (exp milk, human/ and exp secretion/) or exp fertility/ or exp infertility/ or exp reproduction/ or exp fetus/ or exp embryonic structures/ or terat*.ti,ab,kf. or drug efficacy.ti,ab,kf. or therapeutic efficacy.ti,ab,kf. or drug withdrawal.ti,ab, kf. or exp medication errors/ or exp death/ or death*.ti,ab,kf. or fatal*.ti,ab,kf. or exp drug interactions/ or exp carcinogens/ or carcinogen*.ti,ab,kf. or mutagen*.ti,ab,kf. or exp "off-label use"/ or exp occupational exposure/ or toxicity.fs. or toxic*.ti,ab,kf. or pharmacotox*.ti,ab,kf. or neurotox*.ti,ab,kf. or cardiotox*.ti,ab,kf. or nephrotox*.ti,ab,kf. or immunotox*.ti,ab,kf. or hepatotox*.ti,ab,kf. or cytotox*.ti,ab,kf. or immunocytotox*.ti,ab,kf. or intoxicat*.ti,ab,kf. or exp "congenital, hereditary, and neonatal diseases and abnormalities"/ or drug treatment failure.ti,ab,kf. or drug toxicity.ti,ab,kf. or exp case report/ or case report?.ti,ab,kf. or exp environmental exposure/ or treatment contraindication.ti,ab,kf. or exp contraindications, drug/ or exp "wounds and injuries"/ or suicid*.ti,ab,kf. or exp poisoning/ or poisoning.fs. or exp drug tolerance/ or exp treatment failure/ or exp drug resistance/ or exp substance-related disorders/ or exp covid-19/ or (COVID-19 or SARS-CoV-2).rx,px,ox,rn. or (COVID-19 or COVID-19 serotherapy or ORF7b protein, SARS-CoV-2 or ORF6 protein, SARS-CoV-2 or ORF8 protein, SARS-CoV-2 or pediatric multisystem inflammatory disease, COVID-19 related or envelope protein, SARS-CoV-2 or ORF7a protein, SARS-CoV-2 or spike protein, SARS-CoV-2 or ORF3a protein, SARS-CoV-2 or COVID-19 drug treatment or severe acute respiratory syndrome coronavirus 2 or membrane protein, SARS-CoV-2 or ORF1ab polyprotein, SARS-CoV-2 or nucleocapsid protein, Coronavirus or COVID-19 vaccine or COVID-19 diagnostic testing).os,ps,rn,rs. or (coronaviridae or coronavirinae or betacoronavirus or 'novel corona*' or covi* or 'covid 19' or 'covi 19' or covid19 or covi19 or covid19 or covi-19 or '2019 ncov' or 2019ncov or 2019- ncov or ncov or cov-2 or cov2 or 'cov 2' or sarscov2 or sars-cov-2 or 'sars cov 2' or sarscov2 or sarscov-2 or 'sars cov2' or 'sarscov 2' or 'sars-cov 2' or 'sars cov-2' or 'novel cov').ti,ab,kf. or (coronaviridae or coronavirinae or betacoronavirus or 'novel corona*' or covi* or 'covid 19' or 'covi 19' or covid19 or covi19 or covid19 or covi-19 or '2019 ncov' or 2019ncov or 2019- ncov or ncov or cov-2 or cov2 or 'cov 2' or sarscov2 or sars-cov-2 or 'sars cov 2' or sarscov2 or sarscov-2 or 'sars cov2' or 'sarscov 2' or 'sars-cov 2' or 'sars cov-2' or 'novel cov' or (wuhan and (virus or corona* or covi*)) or ((wuhan or hubei or huanan) and ('severe acute respiratory' or pneumonia or sars))).ti,ab,kf.
exp adverse drug reaction/ or adverse.ti,ab,kw. or side effect?.ti,ab,kw. or side effect.fs. or exp drug overdose/ or overdos*.ti,ab,kw. or exp drug misuse/ or misus*.ti,ab,kw. or exp drug abuse/ or exp substance abuse/ or abus*.ti,ab,kw. or exp pregnancy/ or pregnan*.ti,ab,kw. or exp pregnancy complications/ or exp lactation/ or exp breast feeding/ or (exp milk human/ and exp secretion/) or exp fertility/ or exp infertility/ or exp reproduction/ or exp fetus/ or exp embryo/ or terat*.ti,ab,kw. or exp drug efficacy/ or exp drug withdrawal/ or exp medication error/ or exp death/ or death*.ti,ab,kw. or fatal*.ti,ab,kw. or exp drug interaction/ or exp carcinogenicity/ or carcinogen*.ti,ab,kw. or mutagen*.ti,ab,kw. or exp 'off label drug use'/ or exp occupational exposure/ or exp toxicity/ or toxic*.ti,ab,kw. or pharmacotox*.ti,ab,kw. or neurotox*.ti,ab,kw. or cardiotox*.ti,ab,kw. or nephrotox*.ti,ab,kw. or immunotox*.ti,ab,kw. or hepatotox*.ti,ab,kw. or cytotox*.ti,ab,kw. or immunocytotox*.ti,ab,kw. or exp intoxication/ or exp congenital disorder/ or exp drug treatment failure/ or exp case report/ or case report?.ti,ab,kw. or exp environmental exposure/ or exp treatment contraindication/ or exp drug contraindication/ or exp injury/ or suicid*.ti,ab,kw. or exp poisoning/ or exp drug tolerance/ or exp treatment failure/ or exp drug resistance/ or exp substance-related disorders/ or drug resistance.fs. or (coronavirus or 'corona virus' or coronavirus).ti,ab,kw. or exp 'coronavirus disease 2019'/ or exp 'severe acute respiratory syndrome coronavirus 2'/ or coronaviridae.ti,ab,kw. or coronavirinae.ti,ab,kw. or betacoronavirus.ti,ab,kw. or 'novel corona*'.ti,ab,kw. or covi*.ti,ab,kw. or 'covid 19'.ti,ab,kw. or 'covi 19'.ti,ab,kw. or covid19.ti,ab,kw. or covi19.ti,ab,kw. or covid19.ti,ab,kw. or covi-19.ti,ab,kw. or '2019 ncov'.ti,ab,kw. or 2019ncov.ti,ab,kw. or 2019- ncov.ti,ab,kw. or ncov.ti,ab,kw. or cov-2.ti,ab,kw. or cov2.ti,ab,kw. or 'cov 2'.ti,ab,kw. or sarscov2.ti,ab,kw. or sars-cov-2.ti,ab,kw. or 'sars cov 2'.ti,ab,kw. or sarscov2.ti,ab,kw. or sarscov-2.ti,ab,kw. or 'sars cov2'.ti,ab,kw. or 'sarscov 2'.ti,ab,kw. or 'sars-cov 2'.ti,ab,kw. or 'sars cov-2'.ti,ab,kw. or 'novel cov'.ti,ab,kw. or (wuhan and (virus or corona* or covi*)).ti,ab,kw. or ((wuhan or hubei or huanan) and ('severe acute respiratory' or pneumonia or sars)).ti,ab,kw.
(ae or si or to or co).fs.
(safe or safety).ti,ab.
side effect$.ti,ab.
((adverse or undesirable or harm$ or serious or toxic) adj3 (effect$ or reaction$ or event$ or outcome$)).ti,ab.
exp adverse drug reaction/
exp drug toxicity/
exp intoxication/
exp drug safety/
exp drug monitoring/
exp drug hypersensitivity/
exp postmarketing surveillance/
exp drug surveillance program/
exp phase iv clinical trial/
(toxicity or complication$ or noxious or tolerability).ti,ab.
exp postoperative complication/
exp Peroperative Complication/
or/1-16
exp "Drug-Related Side Effects and Adverse Reactions"/or adverse.ti,ab,kf. or side effect?.ti,ab,kf. or adverse effects.fs. or exp drug overdose/ or overdos*.ti,ab,kf. or exp drug misuse/ or misus*.ti,ab,kf. or exp Substance-Related Disorders/ or abus*.ti,ab,kf. or exp pregnancy/ or pregnan.ti,ab,kf. or exp pregnancy complications/ or exp lactation/ or exp lactation disorders/ or exp breast feeding/ or (exp milk, human/ and exp secretion/) or exp fertility/ or exp infertility/ or exp reproduction/ or exp fetus/ or exp embryonic structures/ or terat*.ti,ab,kf. or drug efficacy.ti,ab,kf. or therapeutic efficacy.ti,ab,kf. or drug withdrawal.ti,ab,kf. or exp medication errors/ or exp death/ or death*.ti,ab,kf. or fatal*.ti,ab,kf. or exp drug interactions/ or exp carcinogens/ or carcinogen*.ti,ab,kf. or mutagen*.ti,ab,kf. or exp "Off-Label Use"/ or exp occupational exposure/ or toxicity.fs. or toxic*.ti,ab,kf. or pharmacotox*.ti,ab,kf. or neurotox*.ti,ab,kf. or cardiotox*.ti,ab,kf. or nephrotox*.ti,ab,kf. or immunotox*.ti,ab,kf. or hepatotox*.ti,ab,kf. or cytotox*.ti,ab,kf. or immunocytotox*.ti,ab,kf. or intoxicat*.ti,ab,kf. or exp "Congenital, Hereditary, and Neonatal Diseases and Abnormalities"/ or drug treatment failure.ti,ab,kf. or drug toxicity.ti,ab,kf. or exp case report/ or case report?.ti,ab,kf. or exp environmental exposure/ or treatment contraindication.ti,ab,kf. or exp contraindications, drug/ or exp "Wounds and Injuries"/ or suicid*.ti,ab,kf. or exp poisoning/ or poisoning.fs. or exp drug tolerance/ or exp treatment failure/ or exp drug resistance/ or exp substance-related disorders/
exp adverse drug reaction/ or
adverse.ti,ab,kw. or
side effect?. ti,ab,kw. or
side effect.fs. or
exp drug overdose/ or
overdos*.ti,ab,kw. or
exp drug misuse/ or
misus*.ti,ab,kw. or
exp drug abuse/ or
exp substance abuse/ or
abus*.ti,ab,kw. or
exp pregnancy'/ or
pregnan.ti,ab,kw. or
exp pregnancy complications/ or
exp lactation/ or
exp breast feeding/ or
(exp milk human/ and exp secretion/) or
exp fertility/ or
exp infertility/ or
exp reproduction/ or
exp fetus/ or
exp embryo/ or
terat*.ti,ab,kw. or
exp drug efficacy/ or
exp drug withdrawal/ or
exp medication error/ or
exp death/ or
death*.ti,ab,kw. or
fatal*.ti,ab,kw. or
exp drug interaction/ or
exp carcinogenicity/ or
carcinogen*.ti,ab,kw. or
mutagen*.ti,ab,kw. or
exp 'off label drug use'/ or
exp occupational exposure/ or
exp toxicity'/ or
toxic*.ti,ab,kw. or
pharmacotox*.ti,ab,kw. or
neurotox*.ti,ab,kw. or
cardiotox*.ti,ab,kw. or
nephrotox*.ti,ab,kw. or
immunotox*.ti,ab,kw. or
hepatotox*.ti,ab,kw. or
cytotox*.ti,ab,kw. or
immunocytotox*.ti,ab,kw. or
exp intoxication/ or
exp congenital disorder/ or
exp drug treatment failure/ or
exp case report/ or
case report?.ti,ab,kw. or
exp environmental exposure/ or
exp treatment contraindication/ or
exp drug contraindication/ or
exp injury/ or
suicid*.ti,ab,kw. or
exp poisoning/ or
exp drug tolerance/ or
exp treatment failure/ or
exp drug resistance/ or
exp substance-related disorders/ or
drug resistance.fs.
exp *"Drug-Related Side Effects and Adverse Reactions"/or adverse.ti,kf. or side effect?.ti,kf. or adverse effects.fs. or exp *drug overdose/ or overdos*.ti,kf. or exp *drug misuse/ or misus*.ti,kf. or exp *Substance-Related Disorders/ or abus*.ti,kf. or exp *pregnancy/ or pregnan.ti,kf. or exp *pregnancy complications/ or exp *lactation/ or exp *lactation disorders/ or exp *breast feeding/ or (exp milk, human/ and exp secretion/) or exp *fertility/ or exp *infertility/ or exp *reproduction/ or exp *fetus/ or exp *embryonic structures/ or terat*.ti,kf. or drug efficacy.ti,kf. or therapeutic efficacy.ti,kf. or drug withdrawal.ti,kf. or exp *medication errors/ or exp *death/ or death*.ti,kf. or fatal*.ti,kf. or exp *drug interactions/ or exp *carcinogens/ or carcinogen*.ti,kf. or mutagen*.ti,kf. or exp *"Off-Label Use"/ or exp *occupational exposure/ or toxicity.fs. or toxic*.ti,kf. or pharmacotox*.ti,kf. or neurotox*.ti,kf. or cardiotox*.ti,kf. or nephrotox*.ti,kf. or immunotox*.ti,kf. or hepatotox*.ti,kf. or cytotox*.ti,kf. or immunocytotox*.ti,kf. or intoxicat*.ti,kf. or exp *"Congenital, Hereditary, and Neonatal Diseases and Abnormalities"/ or drug treatment failure.ti,kf. or drug toxicity.ti,kf. or exp *case report/ or case report?.ti,kf. or exp *environmental exposure/ or treatment contraindication.ti,kf. or exp *contraindications, drug/ or exp *"Wounds and Injuries"/ or suicid*.ti,kf. or exp *poisoning/ or poisoning.fs. or exp *drug tolerance/ or exp *treatment failure/ or exp *drug resistance/ or exp *substance-related disorders/
exp *adverse drug reaction/ OR
adverse.ti,kw. OR
side effect?.ti,kw. OR
side effect.fs OR
exp *drug overdose/ OR
overdos*.ti,kw. OR
exp *drug misuse/ OR
misus*.ti,kw. OR
exp *drug abuse/ OR
exp *substance abuse/ OR
abus*.ti,kw. OR
exp *pregnancy'/ OR
pregnan.ti,kw. OR
exp *pregnancy complications/ OR
exp *lactation/ OR
exp *breast feeding/ OR
(exp *milk human/ AND exp *secretion/) OR
exp *fertility/ OR
exp *infertility/ OR
exp *reproduction/ OR
exp *fetus/ OR
exp *embryo/ OR
terat*ti,kw. OR
exp *drug efficacy/ OR
exp *drug withdrawal/ OR
exp *medication error/ OR
exp *death/ OR
death*.ti,kw. OR
fatal*.ti,kw. OR
exp *drug interaction/ OR
exp *carcinogenicity/ OR
carcinogen*.ti,kw. OR
mutagen*.ti,kw. OR
exp *'off label drug use'/ OR
exp *occupational exposure/ OR
exp *toxicity'/ OR
toxic*.ti,kw. OR
pharmacotox*.ti,kw. OR
neurotox*.ti,kw. OR
cardiotox*.ti,kw. OR
nephrotox*.ti,kw. OR
immunotox*.ti,kw. OR
hepatotox*.ti,kw. OR
cytotox*.ti,kw. OR
immunocytotox*.ti,kw. OR
exp *intoxication/ OR
exp *congenital disorder/ OR
exp *drug treatment failure/ OR
exp *br report/ OR
br report?.ti,kw. OR
exp *environmental exposure/ OR
exp *treatment contraindication/ OR
exp *drug contraindication/ OR
exp *injury/ OR
suicid*.ti,kw. OR
exp *poisoning/ OR
exp *drug tolerance/ OR
exp *treatment failure/ OR
exp *drug resistance/ OR
exp *substance-related disorders/ OR
drug resistance.fs
adverse drug reaction.fs
drug interactionor drug therapy.fs
drug toxicity.fs
pharmaceutics.fs
pharmacoeconomics.fs
pharmacokinetics.fs
adverse effects.fs
contraindications.fs
drug effects.fs
pharmacokinetics.fs
poisoning.fs
toxicity.fs
or/1-12
exp adverse drug reaction/ exp drug overdose/
exp drug misuse/
exp drug abuse/
exp pregnancy/
exp pregnancy complications/
exp lactation/
exp breast feeding/
(exp milk human/ and exp secretion/)
exp fertility/
exp infertility/
exp reproduction/
exp fetus/
exp embryo/
exp medication error/
exp death/
exp drug interaction/
exp occupational exposure/
exp congenital disorder/
exp drug treatment failure/
exp case report/
exp environmental exposure/
exp injury/
exp poisoning/
exp drug tolerance/
exp drug resistance/
exp substance-related disorders/
exp drug resistance/
exp toxic actions/
exp drug eruptions/ or/14-50
adverse.mp
side effect*.mp
overdose*.mp
misus*.mp
pregnan* .mp
drug withdrawal*.mp
terat*.mp
death*.mp
fatal*.mp
carcinogen*.mp
mutagen*.mp
toxic*.mp
pharmacotox*.mp
neurotox*.mp
cardiotox*.mp
nephrotox*.mp
immunotox*.mp
hepatotox*.mp
cytotox*.mp
immunocytotox*.mp
case report*.mp
suicide*.mp.
or/52-73
13 OR 51 OR 74
adverse drug reaction.fs
drug interactionor drug therapy.fs
drug toxicity.fs
pharmaceutics.fs
pharmacoeconomics.fs
pharmacokinetics.fs
adverse effects.fs
contraindications.fs
drug effects.fs
pharmacokinetics.fs
poisoning.fs
toxicity.fs
or/1-12
exp adverse drug reaction/ exp drug overdose/
exp drug misuse/
exp drug abuse/
exp pregnancy/
exp pregnancy complications/
exp lactation/
exp breast feeding/
(exp milk human/ and exp secretion/)
exp fertility/
exp infertility/
exp reproduction/
exp fetus/
exp embryo/
exp drug efficacy/
exp medication error/
exp death/
exp drug interaction/
exp carcinogenicity/
exp "off label drug use"/
exp occupational exposure/
exp toxicity/
exp intoxication/
exp congenital disorder/
exp drug treatment failure/
exp case report/
exp environmental exposure/
exp treatment contraindication/
exp drug contraindication/
exp injury/
exp poisoning/
exp drug tolerance/
exp treatment failure/
exp drug resistance/
exp substance-related disorders/
exp drug resistance/
exp toxic actions/
exp drug eruptions/ or/14-51
adverse.mp
side effect*.mp
overdose*.mp
misus*.mp
pregnan* .mp
drug withdrawal*.mp
terat*.mp
death*.mp
fatal*.mp
carcinogen*.mp
mutagen*.mp
toxic*.mp
pharmacotox*.mp
neurotox*.mp
cardiotox*.mp
nephrotox*.mp
immunotox*.mp
hepatotox*.mp
cytotox*.mp
immunocytotox*.mp
case report*.mp
suicide*.mp.
or/53-74
13 OR 52 OR 75
Case Reports/
Organizational Case Studies/
Qualitative Research/
qualitative research*.mp.
qualitative stud*.mp.
action research.mp.
Community-Based Participatory Research/
participatory research.mp.
case stud*.mp.
ethno*.mp.
grounded theory.mp.
phenomeno*.mp.
Narration/
narrative*.mp.
biograph*.mp.
Autobiography/
Autobiograph*.mp.
documentar*.mp.
qualitative synthes*.mp.
active feedback.mp.
conversation*.mp.
discourse*.mp.
thematic.mp.
qualitative data.mp.
key informant*.mp.
Focus Groups/
focus group*.mp.
case report*.mp.
Interview/
interview*.mp.
Observation/
observer*.mp.
visual data.mp.
(audio adj record*).mp.
Anthropology, Cultural/
experience*.mp.
or/1-36
exp clinical trial/
exp Research Design/
random allocation/
double-blind method/
Single-Blind Method/
Placebos/
Cross-Over Studies/
or/38-44
(clinic* adj25 trial*).mp.
random*.mp.
control*.mp.
(latin adj square).mp.
placebo*.mp.
or/46-50
Comparative Study/
comparative stud*.mp.
Validation Studies/
validation stud*.mp.
evaluation studies/
evaluation stud*.mp.
Follow-Up Studies/
followup.mp.
follow-up.mp.
Prospective Studies/
Cross-Over Studies/
cross over.mp.
crossover.mp.
prospective*.mp.
volunteer*.mp.
or/52-66
singl*.mp.
doubl*.mp.
trebl*.mp.
tripl*.mp.
or/68-71
mask*.mp.
blind*.mp.
73 or 74
72 and 75
45 or 51 or 67 or 76
Cohort Studies/
Case-Control Studies/
Cross-Sectional Studies/
Health Surveys/
Health Care Surveys/
Risk/
Incidence/
Prevalence/
Mortality/
cohort*.mp.
case-control.mp.
cross sectional.mp
(health* adj2 survey*).mp.
risk.mp.
incidence.mp.
prevalence.mp.
mortality.tw.
case series.mp.
time series.mp.
before and after.mp.
prognos*.mp.
predict*.mp.
course*.mp.
or/78-100
(mixed adj5 method*).mp.
multimethod*.mp.
(multiple adj5 method*).mp.
or/102-104
qualitative.mp.
Qualitative Research/
quantitative.mp.
106 or 107
108 and 109
105 or 110
37 or 77 or 101 or 111
112 not (letter or comment or editorial or newspaper article).pt.
113 not (exp animals/ not humans.sh.)
